Condensins: universal organizers of chromosomes with diverse functions
نویسندگان
چکیده
منابع مشابه
Diverse mitotic and interphase functions of condensins in Drosophila.
The condensin complex has been implicated in the higher-order organization of mitotic chromosomes in a host of model eukaryotes from yeasts to flies and vertebrates. Although chromosomes paradoxically appear to condense in condensin mutants, chromatids are not properly resolved, resulting in chromosome segregation defects during anaphase. We have examined the role of different condensin complex...
متن کاملUniversal Approximator Property of the Space of Hyperbolic Tangent Functions
In this paper, first the space of hyperbolic tangent functions is introduced and then the universal approximator property of this space is proved. In fact, by using this space, any nonlinear continuous function can be uniformly approximated with any degree of accuracy. Also, as an application, this space of functions is utilized to design feedback control for a nonlinear dynamical system.
متن کاملCohesins and condensins orchestrate the 4D dynamics of yeast chromosomes during the cell cycle
Duplication and segregation of chromosomes involves dynamic reorganization of their internal structure by conserved architectural proteins, including the structural maintenance of chromosomes (SMC) complexes cohesin and condensin. Despite active investigation of the roles of these factors, a genome-wide view of dynamic chromosome architecture at both small and large scale during cell division i...
متن کاملCondensins I and II are essential for construction of bivalent chromosomes in mouse oocytes
In many eukaryotes, condensins I and II associate with chromosomes in an ordered fashion during mitosis and play nonoverlapping functions in their assembly and segregation. Here we report for the first time the spatiotemporal dynamics and functions of the two condensin complexes during meiotic divisions in mouse oocytes. At the germinal vesicle stage (prophase I), condensin I is present in the ...
متن کاملHEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions.
HEAT repeats correspond to tandemly arranged curlicue-like structures that appear to serve as flexible scaffolding on which other components can assemble. Using sensitive sequence analysis techniques we detected HEAT repeats in various chromosome-associated proteins, including four families of proteins associated with condensins and cohesins, which are nuclear complexes that contain structural ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genes & Development
سال: 2012
ISSN: 0890-9369
DOI: 10.1101/gad.194746.112